| Greater Horizons | Kansas City | $15,000 | 3,017 | $1.9B |
| Greater Kansas City Community Foundation | Kansas City | $20,000 | 2,246 | $1.3B |
| St Louis Community Foundation Inc | St Louis | $20,000 | 1,372 | $302.0M |
| Community Foundation of the Ozarks Inc | Springfield | $15,662 | 1,104 | $87.6M |
| Veterans United Foundation | Columbia | $10,000 | 760 | $68.5M |
| Midway USA Foundation Inc | Columbia | $10,218 | 623 | $30.9M |
| United Way of Greater Kansas City Inc | Kansas City | $21,209 | 503 | $67.2M |
| St Louis Community Foundation | St Louis | $11,126 | 423 | $27.9M |
| Forvis Mazars Foundation | Springfield | $10,000 | 292 | $6.5M |
| Truman Heartland Community Foundation | Independence | $12,000 | 260 | $23.0M |
| Mid-America Arts Alliance | Kansas City | $15,000 | 256 | $7.3M |
| Bass Pro Shops & Cabelas Outdoor Fund | Springfield | $15,000 | 250 | $23.6M |
| Regional Cultural and Performing Arts | St Louis | $15,000 | 247 | $16.2M |
| Youthbridge Community Foundation | Saint Louis | $20,400 | 243 | $50.2M |
| Roman Catholic Foundation of Eastern | St Louis | $15,000 | 181 | $15.8M |
| The Kansas City Royals Foundation | Kansas City | $15,000 | 136 | $6.6M |
| Theater League Inc | Kansas City | $10,000 | 135 | $23.2M |
| The Children's Mercy Hospital | Kansas City | $20,020 | 130 | $35.7M |
| Mhm Support Services | Chesterfield | $15,000 | 127 | $6.3M |
| Masonic Home of Missouri | Columbia | $9,000 | 118 | $3.1M |
| National Council of the US Society of | Maryland Heights | $13,780 | 109 | $7.3M |
| Oracle Health Foundation | Kansas City | $11,790 | 108 | $21.6M |
| Bjc Health System | St Louis | $12,500 | 93 | $22.8M |
| The Community Foundation of Northwest Missouriinc | Saint Joseph | $12,500 | 91 | $22.7M |
| Government Employees Health Association Inc | Lees Summit | $10,000 | 84 | $6.1M |
| Regional Business Council | Saint Louis | $20,000 | 75 | $5.8M |
| Metropolitan Arts Council of | Kansas City | $5,500 | 74 | $1.5M |
| Community Capital Fund | Kansas City | $10,000 | 74 | $944K |
| Lockton Cares Inc | Kansas City | $15,400 | 72 | $1.9M |
| St John Health System Inc | St Louis | $10,000 | 66 | $6.1M |
| Boone Electric Community Trust | Columbia | $8,834 | 63 | $993K |
| Missouri Sports Hall of Fame | Springfield | $13,559 | 61 | $2.7M |
| Ssm Health Care of Oklahoma Inc | St Louis | $20,000 | 61 | $4.2M |
| Combat Veterans Motorcycle Association | Liberty | $10,000 | 58 | $545K |
| Missouri United Methodist Foundation | Columbia | $14,790 | 57 | $3.4M |
| National Rural Health Association | Kansas City | $15,000 | 56 | $9.7M |
| Bjc Health System Group Return | St Louis | $10,000 | 55 | $9.5M |
| Community Foundation of Central Mo | Columbia | $19,200 | 50 | $9.2M |
| After the Harvest | Kansas City | $11,836 | 49 | $10.2M |
| Blues for Kids | St Louis | $13,572 | 48 | $2.2M |
| Head for the Cure Foundation | Kansas City | $15,000 | 47 | $3.3M |
| Mobile Health Clinics Association | St Louis | $12,500 | 47 | $726K |
| Heartland Regional Medical Center | St Joseph | $20,400 | 46 | $7.0M |
| Saint Thomas West Hospital | St Louis | $16,000 | 46 | $22.1M |
| The Greater St Louis | St Louis | $10,000 | 45 | $812K |
| Mercy Health Springfield Communities | Springfield | $11,200 | 45 | $2.3M |
| Staenberg Family Foundation | Saint Louis | $18,000 | 44 | $4.4M |
| St Vincent Health Inc | St Louis | $20,000 | 43 | $4.9M |
| Franklin County Area United Way Inc | Washington | $21,500 | 43 | $5.0M |
| Pi Beta Phi Foundation | Town Country | $10,000 | 42 | $7.6M |
| Esco Technologies Foundation | St Louis | $10,000 | 41 | $1.2M |
| Ssm Health Care Corporation | St Louis | $10,000 | 41 | $1.1M |
| Skaggs Foundation | Branson | $17,077 | 40 | $6.1M |
| Missouri Humanities Council | Kansas City | $10,000 | 40 | $3.4M |
| St Louis Cardinals Community Fund | St Louis | $23,082 | 40 | $3.2M |
| St Mary's Health Inc | St Louis | $16,000 | 39 | $4.0M |
| Greater St Louis Inc | St Louis | $10,000 | 39 | $1.8M |
| Suburban Journals Old Newsboy's Fund | St Louis | $5,000 | 39 | $801K |
| Missouri Baptist Foundation | Jefferson City | $11,200 | 36 | $1.8M |
| Disabled American Veterans | Kirksville | $10,000 | 35 | $1.1M |
| The St Louis Men's Group Against Cancer | St Louis | $10,000 | 34 | $1.4M |
| Mccarthy Holdings Charitable | St Louis | $15,000 | 34 | $1.7M |
| Acruxkc | Kansas City | $12,500 | 33 | $1.7M |
| Caring Communities Inc | Jefferson City | $19,257 | 33 | $5.4M |
| International Brotherhood of | Kansas City | $10,000 | 32 | $1.4M |
| Lake of the Ozarks Shootout Inc | Lake Ozark | $14,387 | 31 | $2.0M |
| Mid America Assistance Coalition | Kansas City | $6,592 | 31 | $27.1M |
| Ssm Health Care of Wisconsin Inc | St Louis | $19,835 | 30 | $3.0M |
| Optimist International Foundation | St Louis | $10,900 | 29 | $1.0M |
| The Giving Branch Foundation | Columbia | $10,139 | 29 | $688K |
| Ascension Providence | St Louis | $22,255 | 28 | $3.7M |
| Mercy Hospitals East Communities | St Louis | $18,500 | 26 | $12.2M |
| Missouri Universal Service Fund | Jefferson City | $17,114 | 26 | $3.1M |
| Kansas City Soccer Foundation | Kansas City | $12,250 | 25 | $834K |
| The Home Builders Charitable Foundation | St Louis | $15,000 | 25 | $907K |
| One Classroom | St Louis | $14,160 | 25 | $1.5M |
| United Way of Southeast Missouri | Cape Girardeau | $14,432 | 24 | $1.8M |
| Missouri Incutech Foundation | Rolla | $16,500 | 24 | $1.2M |
| Webster Electric Foundation | Marshfield | $10,000 | 24 | $403K |
| Mercy Health Southwest Missourikansas | Joplin | $11,500 | 22 | $1.3M |
| Beta Sigma Phi Charitable Foundation | Kansas City | $10,000 | 21 | $450K |
| Economic Development Corporation of | Kansas City | $10,000 | 21 | $7.0M |
| Presence Central and Suburban Hospitals Network | St Louis | $11,500 | 20 | $43.9M |
| Generate Health Stl | Saint Louis | $15,100 | 20 | $1.2M |
| Springfield Regional Arts Council | Springfield | $10,000 | 20 | $354K |